The Cosmelan® Depigmentation Lab

Welcome to the specialised Cosmelan® Depigmentation Lab at Liverpool Skin Lab, an elite, doctor-led clinical sanctuary centring on advanced epidermal remodelling and medical pigment correction. Directed exclusively by GMC-registered Specialty Doctor Dr Carmen Ranjith (MBChB, PGCert), our clinic is a formally accredited Mesoestetic® treatment provider.

We reject superficial high-street beauty facials. Instead, we deliver the world’s leading medical-grade depigmentation chemistry, backed by over 40 years of continuous scientific perfection by Mesoestetic® laboratories, to eliminate complex skin concerns at a deep cellular level.

The Science of Cellular Depigmentation

Hyperpigmentation is a complex cellular defence response triggered by hormonal shifts, inflammation, UV trauma, or metabolic changes. Standard cosmetic brighteners fail because they only treat the surface cells. The Cosmelan® formula works through a dual-action mechanism: Corrective (shedding existing dark spots) and Regulative (permanently downregulating the cellular pathways that produce new pigment).

Our custom-calibrated clinical protocols actively intercept and treat four primary dermatological conditions:

Melasma & Chloasma: Stubborn, deep-seated hormonal pigmentation often resistant to standard skincare. Cosmelan® deactivates tyrosinase—the key enzyme responsible for melanin overproduction—at the molecular level, clearing dark patches on the cheeks, forehead, and upper lip.
Post-Inflammatory Hyperpigmentation (PIH): Dark or dusky marks left behind following acne breakouts, physical skin trauma, or aggressive beauty treatments. Dr Ranjith specialises in using this system to safely clear PIH across higher Fitzpatrick skin types (skin of colour) without triggering inflammatory rebound.
Solar Lentigo (Sun Damage & Age Spots): Localised ultraviolet damage that leads to fixed, deep brown sun spots across the face, neck, and chest. The peeling phase safely shatters these dense melanin clusters, forcing the skin to regenerate fresh, radiant, unblemished epidermal cells rapidly.
Ephelides (Freckles): Fragmented genetic pigment deposits that darken with sun exposure, which are smoothly unified to achieve a flawless, homogeneous skin tone.

The Master Active Ingredients & How They Repair Your Skin

The unmatched efficacy of the Mesoestetic® formula lies in its synergy of highly concentrated, medical-grade active molecules working simultaneously across multiple dermal layers:

Azelaic Acid & Kojic Acid: Direct tyrosinase inhibitors that block melanin synthesis pathways, preventing overactive melanocytes from producing new pigment.
Phytic Acid & Ascorbic Acid (Pure Vitamin C): Powerful biological antioxidants that chelate copper and deeply neutralise free radicals, instantly brightening dull complexions and protecting the skin barrier from future UV degradation.
Retinol & Salicylic Acid: Active cellular stimulators that accelerate epidermal cell turnover. By peeling away the outer, stained layers of the skin, they force deep melanin deposits to rise and shed, while smoothing fine lines and treating active acne.
Liquorice Extract & Aloe Vera: High-grade anti-inflammatories that soothe vascular pathways, calm melanocyte irritability, and protect the skin barrier during the intensive cellular renewal phase.

Our Exclusive Cosmelan® Treatment Packages & Cost Savings

To highlight the exceptional financial value of our doctor-led clinic, we have itemised the exact Recommended Retail Price (RRP) for purchasing these medical-grade items individually versus our bundled clinical treatment options.

The Baseline Retail Cost (Bought Individually)

In-House 3 installments available for Cosmelan Method and System

If you were to purchase the essential components of the home-care continuity system separately as individual retail products, the standard retail costs are:

Cosmelan 2 Maintenance Cream (30g): £139.95
Melan Recovery Soothing Cream (50ml): £64.45
Mesoprotech Melan 130+ Pigment Control (50ml): £49.96
Total Individual Retail Product Cost: £254.36

Please note: the following is an estimate of how many products you'll need during your Cosmelan 6-month protocol. You may need to purchase additional products. For best results, we recommend completing the full protocol.

1. The Cosmelan® Home Care Pack

Designed for patients seeking an autonomous, premium home-treatment regimen to manage mild pigment changes or maintain professional results.

What is included: A complete, full-sized Mesoestetic® Home Continuity Kit containing Cosmelan 2 (30g), Melan Recovery (50ml), and Melan 130+ Pigment Control SPF (50ml).
Cost if purchased individually: £254.36
Standard RRP for the Boxed Pack: £219.95
Your Exclusive Clinic Price: £129.95
✨ Your Total Financial Saving: £124.41 off the individual product cost (and £90.00 off the standard retail pack RRP).

2. The Core Cosmelan® Method Protocol

Our most popular, comprehensive doctor-led intervention for deep-seated melasma, sun damage, and advanced hyperpigmentation.

What is Included:
- Full 45-minute medical history review, diagnostic skin mapping, and clinical pre-treatment preparation.
- In-clinic application of the high-potency Cosmelan 1 Medical Mask and professional Post-Peel Neutralising Spray.
- Three scheduled clinical follow-up reviews for tracking and skin auditing with Dr Carmen Ranjith.
- The complete, full-sized Mesoestetic® Home Care Pack (Cosmelan 2, Melan Recovery, and Melan 130+ SPF) to continue your dermal regulation at home for 6 weeks.
- You would need to buy 3 additional Cosmelan Home Packs for £129.95 each.
Total Combined Value (In-Clinic Medical Phase + Individual Retail Products): £1,254.36
Your Exclusive Clinic Price: £1200 Now £995
✨ Your Total Financial Saving: £464.36

3. The Advanced Cosmelan® System

The ultimate, multi-level clinical solution engineered for historic, highly resistant dermal pigmentation compounded by advanced structural tissue ageing.

What is Included:
- Includes the complete Core Cosmelan® Method Protocol (In-clinic medical mask application, full 6-month home care pack, and 3 clinical reviews).
- Enhanced with two preparatory chemical skin-priming treatments administered in-clinic 14 days before your main mask application to fully prep the epidermal mantle and optimise chemical absorption.
- Includes an additional targeted post-peel cellular restoration treatment.
Total Combined Value (In-Clinic Peels + Mask Phase + Individual Retail Products): £1,554.36
Your Exclusive Clinic Price: £1800 Now £1250
✨ Your Total Financial Saving: £909.36